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Delivery of intravenously administered antibodies targeting Alzheimer's disease-relevant tau species into the brain based on receptor-mediated transcytosis

Morozov, V.G., et al

During the pathological process of NDDs such as AD, PD, and MS, the tight junctions of the BBB gradually loosen due to chronic inflammation, oxidative stress and other factors, and the permeability abnormally increases

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Many mechanisms of senescence escape remain unknown

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